cancer care Because the use of prostate MRI has
cancer care. Because the use of prostate MRI has grown, and is likely to continue expanding, the cost-effectiveness of MRI-driven pathways are increasingly relevant to the sustainability of the practice. Despite initial high costs associated with obtaining and interpreting MRI studies of the prostate, economic modeling studies imply that MRI would be cost-effective if it D-Luciferin resulted in increased utiliza-tion of AS for low and very-low risk PCa.30 The associa-tion identified in our study between MRI use and initial observation may serve as an informative basis for examin-ing strategies to improve the quality of PCa care with the anticipated growing use of this technology.
Acknowledgment. The collection of the California cancer incidence data used in this study was supported by the California Department of Public Health as part of the statewide cancer reporting program mandated by California Health and Safety Code Section 103885; the National Cancer Institute’s Surveil-lance, Epidemiology and End Results (SEER) Program under contract N01-PC-35136 awarded to the Northern California Cancer Center, contract N01-PC-35139 awarded to the Univer-sity of Southern California, and contract N02-PC-15105 awarded to the Public Health Institute; and the Centers for Dis-ease Control and Prevention's National Program of Cancer Reg-istries, under agreement #U55/CCR921930-02 awarded to the Public Health Institute. The ideas and opinions expressed herein are those of the author(s) and endorsement by the State of Cali-fornia, Department of Public Health, the National Cancer Insti-tute, and the Centers for Disease Control and Prevention or their Contractors and Subcontractors is not intended nor should be inferred. The authors acknowledge the efforts of the Applied Research Program, National Cancer Institute; the Office of Research, Development and Information, Centers for Medicare and Medicaid Services; Information Management Services, Inc; and the SEER Program tumor registries in the creation of the SEER-Medicare database. The interpretation and reporting of the SEER-Medicare data are the sole responsibility of the authors. r> SUPPLEMENTARY MATERIALS
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